Environmental

Pathophysiology is that branch in science that deals with the study of the changes in mechanical, physical and biochemical functions brought about by a disease. One such disease that brings pathophysiologcal changes is diabetes. Diabetes pathophysiology therefore deals on the various changes brought by the incidence of diabetes as a disease.  

As there are three types of diabetes, the diabetes pathophysiology will also vary in relation to the symptoms and complications involved in each type of diabetic condition wherein, the gestation type is only a prelude to type 2 diabetes.  

What Recent Studies Show about Diabetes Pathophysiology in the American Population

About 65% of Americans today are considered as overweight and that it is estimated that 1/4 of the US population is suffering from diabetes, which is estimated to be around 21 million Americans.

The US ranks third in the world for having the most number of people afflicted with diabetes, trailing behind India who ranks as number one and China as the second. It is reported that the epidemic is concerned more with obesity being an underlying cause of diabetes.

Those born after the year 2000 are said to be already at risk of developing diabetes and this concerns 33% of the male population, 39% of the female wherein 50% of this will be Hispanic women. Based on assessment of medical facts and figures, the results indicate that cardiovascular diseases will be the eventual cause of fatalities.

Asians who were not among those included in high statistics before has now a high incidence of diabetic suffering population. Where the existence of the American fast food chains being considered, like in Korea where 10% of the population is diagnosed as diabetic.

Diabetes Type 1

The underlying causes of Type 1 diabetes, being genetic disposition, environmental exposure to virus, toxins, stress factors  and how it affects the beta-cells of the pancreas to produce insulin are all likely influences of diabetes pathophysiology in the society or community.

In short, the present day generation acquired their insulin deficiency from parents counted in the previous diabetic statistics. 

With these factors considered, diabetes today commonly occurs from puberty age of 10 to 14 years of age, and the majority of those who developed diabetes type 1 became full-fledge diabetics before they reached the age of 30.

The basic characteristics evident among the sufferers are the symptomatic signs of hyperglycemia or borderline diabetes, intense thirst and unstinted hunger, frequency in urination, weight loss and low energy levels.

Diabetes Type 2

In Diabetes Type 2 where the sufferer is insulin resistant, the changes in the environment caused an individual to gain weight and develop all sorts of fat found in all the wrong places, wherein belly fat is the most harmful. In fact, childhood obesity has grown into epidemic proportions globally and early diagnosis treatment and management is now a global concern.

The genes among these children were not in question but their habits as they grew older as influenced by their current environment have changed. As they enter obesity at an early age, more and more substances are produced by the body to cause insulin resistance. Hence, the current statistics of type 2 diabetes include those belonging to the age range of 10 to 19. 

It is quite evident therefore that eating habits and lifestyle as influenced by a society where children are now more engaged in less activity like video games and virtual recreations. Diabetes pathophysiology can include organ malfunction which may start from the liver resulting to insulin resistance.

Hence, parents who are supposed to be more knowledgeable should become aware of the fact that over feeding their young ones and keeping them confined in front of video consoles are not the best methods of providing a good future for their children.

Alvin Hopkinson is a leading health researcher in the area of natural remedies and diabetes natural treatment. Discover how you can reverse your diabetes for good using proven and effective home remedies, all without using harmful medications or drugs. Visit his site now at http://www.minusdiabetes.com

Read more

Much has been written about pesticides and pollutants as being major contributors to cancers today. According to the National Toxicology Program at the U.S. Department of Health and Human Services, there are 52 chemicals known to contribute to cancers of all kinds in humans and 176 chemicals reasonably anticipated to be human carcinogens. Lung and mammary cancers are the most common types of cancers that are found in animal based studies of potential carcinogens. Despite this data, most experts believe that more relevant environmental risks involve diet, lifestyle, and factors related to a prolonged exposure to estrogens. However, a brief discussion of some proven and unproven chemicals associated with breast cancer risk is worthwhile.

Smoking: Researchers from Albert Einstein College of Medicine in New York examined the association between cigarette smoking and incidence of breast cancer in a cohort of women who had smoked for up to 40 years. The women were subsequently followed for an average of 10.6 years. Their risk of breast cancer was 60% higher than that of women who had never smoked. Among those who smoked 20 cigarettes or more a day for 40 years, the increased risk rose to an 83% increase.

DDT: DDT and its metabolite DDE are weakly estrogenic organochlorine pesticides that accumulate in the food chain and collect in human adipose tissues through the consumption of animal products. Although several studies showed no link when blood DDT levels were checked many years after exposure, a recent study based on samples from blood collected during perinatal periods showed that women heavily exposed to the pesticide DDT during childhood are five times as likely to develop breast cancer later in life.

Other Pesticides: Other pesticides including endosulfan, toxaphene and dieldrin have been implicated as causing breast cancer based on animal studies, but their contribution to human breast cancer is unclear.

Commercial Product Chemicals: A long list of chemicals found in common commercial products have been implicated in breast cancer. This list includes industrial solvents (trichloroethylene, toluene and benzene), plastic water bottles and baby bottles (bisphenol-A), and polyvinyl chloride, a ubiquitous chemical found in food packaging, medical products, appliances, cars and toys. Again, the significance of their contribution to human breast cancer is unclear.

Pollutants: A very well studied group of chemicals collectively called polycyclic aromatic hydrocarbons (PAHs) have also been implicated in breast cancer. The most common sources of these chemicals include charbroiled meat, cigarette smoke, car exhaust, and burning fuel.

Radiation exposure: Mounting evidence suggests that X-ray and gamma-ray exposure may be a significant and causative factor, particularly if the exposure is during childhood or early adulthood. Radiation therapy done for Tuberculosis and dermatologic conditions and radiation exposure from atomic bombs have been proven to cause breast cancer. The most important factor in radiation exposure is the dose of radiation. This is why efforts have been made to decrease the radiation from mammograms by 10-fold. The energy level of the radiation may also be important. Several epidemiologic studies have shown an increased risk of breast cancer among female airline attendants (1.9 fold increased risk). The likely cause for airline attendant’s increased cancer risk is exposure to cosmic radiation (neutrons and gamma rays), which have much higher energy than X-rays.

Read more